antioxydants

systematic review meta-analysis network meta-analysis

Select cardiovascular preventiondiabetes type 2peripheral vascular diseasespost acute coronary syndromes post myocardial infarction All type of patientuncoded clinical condition ***Diabetic patientspatients undergoing dialysisprimary preventionsecondary prevention in patients with CAD       antioxydantvitamine E beta carotenevitamin cvitamin e vs placebo or control      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	All cause death (50)Cardiovascular death (44)cardiovascular events (42)stroke (fatal and non fatal) (33)Coronary event (24)Non fatal MI (23)ischemic stroke (23)Haemmorhagic stroke (19)Non fatal stroke (17)Amputation (6)Coronary death (2)cardiovascular death, MI, stroke (1)new-onset diabetes (1)new-onset atrial fibrillation (1) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	All cause death	Cardiovascular death
cardiovascular prevention
beta carotene
ATBC beta carotene, 1994	beta carotene	placebo			Low risk of bias	-
CARET beta carotene, 1996	beta carotene	placebo			Low risk of bias	negative
SCP beta carotene, 1990	beta carotene	placebo			Low risk of bias	negative
NSCP (Green) beta carotene, 1999	beta carotene	placebo			Low risk of bias	negative
PHS beta carotene, 1996	beta carotene	placebo			Low risk of bias	suggesting
WHS beta carotene, 1999        NCT	beta carotene	placebo			Low risk of bias	negative
WACS beta-caroten, 2007        NCT	beta carotene	placebo			Low risk of bias	negative
ATBC 2nd prev subgroup (b carotene), 1998	beta carotene	placebo			Low risk of bias	negative
vitamin c
WACS vitamin C, 2007        NCT	vitamin C	placebo			Low risk of bias	negative
PHS II vitamin C, 2008    NCT	vitamin C	placebo			Low risk of bias	negative
vitamin e
GISSI, 1999	vitamin E	control			Risk of bias	negative
PPP, 2001	vitamin E	control			Risk of bias	negative
ATBC vitamin E, 1994	vitamin E	placebo			Low risk of bias	suggesting
CHAOS, 1996	vitamin E	placebo			Low risk of bias	suggesting
HOPE, 2000	vitamin E	placebo			Low risk of bias	negative
AREDS, 2001	vitamin E	placebo			Low risk of bias	negative
Linxian, 1993	vitamin E	placebo				negative
WACS vitamin E, 2007        NCT	vitamin E	placebo			Low risk of bias	negative
PHS II vitamin E, 2008    NCT	vitamin E	placebo			Low risk of bias	negative
WHS vitamin E, 2005      NCT	vitamin E	placebo			Low risk of bias	negative
ASAP, 2000	vitamin E	placebo			Low risk of bias	negative
SPACE, 2000	vitamin E	placebo			Low risk of bias	suggesting
HOPE renal insufficiency subgroup, 2004	vitamin E	placebo			Low risk of bias	negative
ATBC 2nd prev subgroup (vitamin E), 1998	vitamin E	placebo			Low risk of bias	negative
peripheral vascular diseases
vitamin e
Livingstone, 1958		placebo				-
Hamilton, 1953		placebo				-