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coronary artery disease
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aspirin
clopidogrel
dipyridamol
ticlopidine
aspirin
clopidogrel
dipyridamol
ticlopidine
vs placebo or control
vs aspirin
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Description
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Characteristics
Method
Risk of bias
References
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NCT results
Non fatal MI (17)
Cardiovascular death (14)
All cause death (12)
cardiovascular events (8)
Non fatal stroke (6)
Non vascular death (6)
Fatal MI (3)
stroke (fatal and non fatal) (3)
Coronary event (1)
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medians
Trial
Studied trt
Control trt
patients
tags
ROB
Trial result
Non fatal MI
Cardiovascular death
coronary artery disease
aspirin
CDPA, 1976
aspirin
placebo
Low risk of bias
negative
-11%
-30%
Cardiff I, 1974
aspirin
placebo
Low risk of bias
negative
Cardiff II, 1979
aspirin
placebo
Low risk of bias
negative
Vogel, 1979
aspirin
placebo
Low risk of bias
suggesting
-53%
-50%
AMIS, 1980
NCT
aspirin
placebo
Low risk of bias
suggesting
-22%
GAMIS, 1980
aspirin
placebo
Low risk of bias
negative
-29%
PARIS, 1980
aspirin
placebo
Low risk of bias
negative
-30%
-18%
JAMIS, 1999
aspirin
placebo
suggesting
-73%
10%
SAPAT, 1992
aspirin
placebo
Low risk of bias
suggesting
-33%
-24%
clopidogrel
CAPRIE, 1996
clopidogrel
aspirin
Low risk of bias
-
ASCET
NCT
clopidogrel
aspirin
Risk of bias
negative
dipyridamol
Atlanta (Sbar), 1967
dipyridamol
control
Low risk of bias
negative
-25%
∞%
Becker, 1967
dipyridamol
control
Low risk of bias
negative
∞%
Wirecki, 1967
dipyridamol
control
Low risk of bias
negative
Igloe, 1970
dipyridamol
placebo
Low risk of bias
-
Zion, 1961
dipyridamol
placebo
Low risk of bias
-
Kinsella, 1962
dipyridamol
placebo
Low risk of bias
-
Leiberman, 1964
dipyridamol
placebo
Low risk of bias
-
Dewar, 1961
dipyridamol
placebo
Low risk of bias
-
Neumann, 1964
dipyridamol
placebo
Low risk of bias
-
Foulds, 1960
dipyridamol
placebo
Low risk of bias
-
PARIS, 1980
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS-II, 1986
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS, 1980
dipyridamol + aspirin
aspirin
Low risk of bias
negative
ticlopidine
Berglund, 1985
ticlopidine
placebo
Low risk of bias
negative
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