| Catheter ablation | ventricular tachycardia in patients with structural heart disease , in all type of patients | vs no ablation | NS | by 45% | NS | by 62% | by 49% | NS | NS | by 39% | | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
|---|
| All cause death | 0.77 [0.34 1.77] | p=1.00 | 0 | 238 | 2 | VTACH, SMASH-VT, | | hospitalisation for cardiovascular causes | 0.55 [0.30 1.00] | p=0.04 | 0 | 110 | 1 | VTACH, | | Syncope | 0.36 [0.07 1.83] | p=1.00 | 0 | 110 | 1 | VTACH, | | ICD events | 0.38 [0.15 0.94] | p=0.04 | 0 | 128 | 1 | SMASH-VT, | | Appropriate ICD shock | 0.51 [0.28 0.94] | p=0.04 | 0 | 238 | 2 | VTACH, SMASH-VT, | | Inappropriate ICD shock | 0.69 [0.18 2.60] | p=1.00 | 0 | 110 | 1 | VTACH, | | all ICD shock (appropriate and inappropriate) | 0.61 [0.28 1.32] | p=1.00 | 0 | 110 | 1 | VTACH, | | VT or VF | 0.61 [0.37 1.00] | p=0.04 | 0 | 110 | 1 | VTACH, |
TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients | Trial | Studied treatment | Control | Patients |
|---|
| VTACH, 2009 | catheter ablation for ventricular tachycardia (VT) plus implantable cardioverter defibrillator | implantable cardioverter defibrillator alone | Patients undergoing implantation of an ICD Patients undergoing implantation of an ICD | | SMASH-VT, 2007 | defibrillator implantation with adjunctive catheter ablation | defibrillator implantation alone | patients with a history of a myocardial infarction undergoing defibrillator implantation for spontaneous ventricular tachycardia or fibrillation |
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