antidiabetic drugs

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Matrix  

Albiglutidediabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Albiglutidediabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Dapagliflozindiabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Dapagliflozindiabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Pioglitazonediabetes type 2, in patients inadequately controlled with insulin vs placebo (add on insulin)

all NS

Alogliptindiabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Alogliptindiabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Linagliptindiabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on SU)

all NS

Linagliptin vs glimepiride (add on MET)

all NS

Linagliptindiabetes type 2, in patients insufficiently controlled on SU vs placebo (add on SU)

all NS

Linagliptindiabetes type 2, in Patients inadequately controlled on MET+SU therapy vs Metformin + sulfonylurea

all NS

Linagliptindiabetes type 2, in patients with insufficient glycaemic control with bitherapy vs Metformin + sulfonylurea

all NS

Linagliptindiabetes type 2, in drug naïve patients vs placebo

all NS

Linagliptindiabetes type 2, in patients inadequately controlled on metformin vs glimepiride (add on MET)

all NS

Saxagliptindiabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Saxagliptin vs sitagliptin (add on MET)

all NS

Saxagliptindiabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Saxagliptin vs placebo (add on TZD)

all NS

Saxagliptin vs sitagliptin (add on MET)

all NS

Saxagliptindiabetes type 2, in in patients inadequately controlled on standard therapy vs placebo (add on current treatment)

all NS

Saxagliptindiabetes type 2, in drug naïve patients vs placebo (monotherapy)

all NS

Saxagliptindiabetes type 2, in patients inadequately controlled with insulin vs placebo (add on insulin)

all NS

Saxagliptindiabetes type 2, in patients inadequately controlled on TZD vs placebo (add on TZD)

all NS

Sitagliptindiabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Sitagliptindiabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Sitagliptin vs placebo (on top PIO)

Adverse events leading to treatment discontinuation by 459% adverse event

Sitagliptindiabetes type 2, in patients with insufficient glycaemic control with bitherapy vs placebo (on-top glimepiride+/- metformine)

all NS

Vildagliptindiabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Vildagliptin vs Sulfonylurea (add on to MET)

all NS

Vildagliptin vs pioglitazone (add on MET)

all NS

Vildagliptindiabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on insulin)

Adverse events leading to treatment discontinuation by 850% adverse event

Vildagliptin vs placebo (add on MET)

all NS

Vildagliptin vs placebo (on top pioglitazone)

all NS

Vildagliptin vs Sulfonylurea (add on to MET)

all NS

Vildagliptin vs pioglitazone (add on MET)

all NS

Vildagliptin vs placebo (add on TZD)

all NS

Vildagliptindiabetes type 2, in patients inadequately controlled with insulin vs placebo (add on insulin)

Adverse events leading to treatment discontinuation by 850% adverse event

Vildagliptindiabetes type 2, in patients inadequately controlled on TZD vs placebo (on top pioglitazone)

all NS

Vildagliptin vs placebo (add on TZD)

all NS

Exenatidediabetes type 2, in patients with insufficient glycaemic control with bitherapy vs weekly exenatide

all NS

Exenatide vs placebo (add on MER+/-SU)

all NS

Exenatide vs placebo (add on MET+/-SU)

all hypoglycemia by 292% adverse event

treatment-emergent adverse events (TEAEs) by 58% adverse event

A CHANGER by 2825% adverse event

vomiting by 7336% adverse event

Exenatide vs placebo (add on SU+/-MET/TZD)

all NS

Exenatide vs placebo (add on SU+MET)

all hypoglycemia by 277% adverse event

A CHANGER by 111% adverse event

vomiting by 219% adverse event

diarrhoea by 110% adverse event

Exenatide vs placebo (add on TZD+/-MET)

A CHANGER by 161% adverse event

vomiting by 1381% adverse event

Exenatide vs insulin (add on SU+MET)

A CHANGER by 563% adverse event

vomiting by 364% adverse event

diarrhoea by 184% adverse event

Exenatide vs insulin (add on SU/MET)

all NS

Exenatide vs insulin BIAsp twice daily add on SU+MET

A CHANGER by 8134% adverse event

vomiting by 366% adverse event

diarrhoea by 371% adverse event

Exenatidediabetes type 2, in patients inadequately controlled with insulin vs placebo (add on insulin)

A CHANGER by 399% adverse event

vomiting by 345% adverse event

diarrhoea by 123% adverse event

Exenatide vs insulin (add on SU+MET)

A CHANGER by 563% adverse event

vomiting by 364% adverse event

diarrhoea by 184% adverse event

Exenatide vs insulin (add on SU/MET)

A CHANGER by 838% adverse event

vomiting by 220% adverse event

Exenatide vs insulin BIAsp twice daily add on SU+MET

A CHANGER by 8134% adverse event

vomiting by 366% adverse event

diarrhoea by 371% adverse event

Exenatide vs insulin glargine

A CHANGER by 857% adverse event

diarrhoea by 139% adverse event

Exenatide vs insulin glargine (add on MET/SU)

all NS

Exenatidediabetes type 2, in Patients inadequately controlled on MET+SU therapy vs placebo (add on SU+MET)

all hypoglycemia by 277% adverse event

A CHANGER by 111% adverse event

vomiting by 219% adverse event

diarrhoea by 110% adverse event

Exenatide vs insulin (add on SU+MET)

A CHANGER by 563% adverse event

vomiting by 364% adverse event

diarrhoea by 184% adverse event

Exenatide vs insulin BIAsp twice daily add on SU+MET

A CHANGER by 8134% adverse event

vomiting by 366% adverse event

diarrhoea by 371% adverse event

Exenatidediabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Exenatide vs placebo (add on MET+/-SU)

all hypoglycemia by 292% adverse event

treatment-emergent adverse events (TEAEs) by 58% adverse event

A CHANGER by 2825% adverse event

vomiting by 7336% adverse event

Exenatidediabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MER+/-SU)

all NS

Exenatide vs placebo (add on MET)

all NS

Exenatide vs placebo (add on MET+/-SU)

all hypoglycemia by 292% adverse event

treatment-emergent adverse events (TEAEs) by 58% adverse event

A CHANGER by 2825% adverse event

vomiting by 7336% adverse event

Exenatide vs placebo (add on SU)

A CHANGER by 436% adverse event

vomiting by 294% adverse event

Exenatide vs exenatide before breakfast and dinner

all NS

Exenatide vs insulin glargine (add on MET/SU)

all NS

Liraglutidediabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Liraglutide vs placebo (add on SU)

A CHANGER by 330% adverse event

Liraglutide vs placebo (add on SU+MET)

A CHANGER by 297% adverse event

diarrhoea by 280% adverse event

Liraglutide vs glimepiride (add on MET)

all NS

Liraglutide vs insulin glargine (add on SU+MET)

A CHANGER by 976% adverse event

vomiting by 1413% adverse event

diarrhoea by 673% adverse event

Liraglutide vs rosiglitazone (add on SU)

all NS

Liraglutide vs glibenclamide

all NS

Liraglutide vs sitagliptin

A CHANGER by 421% adverse event

vomiting by 110% adverse event

diarrhoea by 103% adverse event

Liraglutidediabetes type 2, in patients with insufficient glycaemic control with bitherapy vs placebo (add on TZD+MET)

all NS

Liraglutide vs exenatide on top MET/SU/MET+SU

severe adverse events by 180% adverse event

Liraglutidediabetes type 2, in Patients inadequately controlled on MET+SU therapy vs placebo (add on SU+MET)

A CHANGER by 297% adverse event

diarrhoea by 280% adverse event

Liraglutide vs insulin glargine (add on SU+MET)

A CHANGER by 976% adverse event

vomiting by 1413% adverse event

diarrhoea by 673% adverse event

Liraglutide vs exenatide on top MET/SU/MET+SU

severe adverse events by 180% adverse event

Liraglutidediabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Liraglutide vs glimepiride (add on MET)

all NS

Liraglutide vs sitagliptin

A CHANGER by 421% adverse event

vomiting by 110% adverse event

diarrhoea by 103% adverse event

Taspoglutidediabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Taspoglutide vs placebo

all NS

Taspoglutidediabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Taspoglutide vs placebo

all NS

Lixisenatide diabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Lixisenatide diabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on MET)

all NS

Lixisenatide diabetes type 2, in patients inadequately controlled with insulin vs placebo (add on basal insulin)

all NS

Mitiglinidediabetes type 2, in all types of patients vs nateglinide

all NS

Mitiglinide vs on top insulin glargine

all NS

Mitiglinide vs placebo (on top pioglitazone)

all NS

Mitiglinidediabetes type 2, in patients inadequately controlled on monotherapy vs placebo (on top pioglitazone)

all NS

Nateglinidediabetes type 2, in all types of patients vs repaglinide

all NS

Nateglinide vs placebo

all NS

Nateglinide vs gliclazide (add on MET)

all NS

Nateglinidediabetes type 2, in patients inadequately controlled on metformin vs gliclazide (add on MET)

all NS

Nateglinidediabetes type 2, in patients inadequately controlled on monotherapy vs gliclazide (add on MET)

all NS

Repaglinide diabetes type 2, in all types of patients vs glibenclamide

all NS

Repaglinide vs glipizide

all NS

Repaglinide vs metformin

all NS

Repaglinide vs on top pioglitazone

all NS

Repaglinide vs on top rosiglitazone

all NS

Repaglinide vs on top troglitazone

all NS

Repaglinide vs placebo (on top bedtime NPH-insulin)

all NS

Repaglinide vs control (add on MET)

all NS

Repaglinide vs placebo

all NS

Repaglinide diabetes type 2, in patients inadequately controlled on metformin vs control (add on MET)

all NS

Repaglinide diabetes type 2, in patients inadequately controlled on monotherapy vs control (add on MET)

all NS

Glipizidediabetes type 2, in all types of patients vs control (add on MET)

all NS

Glipizide vs glyburide

all NS

Glipizide vs placebo

all NS

Glipizidediabetes type 2, in patients inadequately controlled on monotherapy vs control (add on MET)

all NS

Glipizide vs glyburide

all NS

Glipizidediabetes type 2, in patients insufficiently controlled on SU vs glyburide

all NS

Glyburidediabetes type 2, in all types of patients vs c (add on MET)

all NS

Glyburide vs control (add on MET)

all NS

Glyburide vs placebo

all NS

Glyburidediabetes type 2, in patients inadequately controlled on monotherapy vs control (add on MET)

all NS

Glyburide vs placebo

all NS

Glimeripidediabetes type 2, in all types of patients vs placebo

all NS

Glimeripide vs placebo (add on insulin)

all NS

Glimeripide vs placebo (add on MET)

all NS

Glimeripide vs gliclazide

all NS

Glimeripide vs glibenclamide

all NS

Glimeripide vs gliclazide or glibenclamide

all NS

Glimeripide vs glimepiride bid

all NS

Glimeripide vs glipizide

all NS

Glimeripide vs glyburide

all NS

Glimeripidediabetes type 2, in patients inadequately controlled on monotherapy vs placebo (add on insulin)

all NS

Glimeripide vs placebo (add on MET)

all NS

Glimeripide vs gliclazide or glibenclamide

all NS

Glimeripidediabetes type 2, in patients inadequately controlled on metformin vs placebo (add on MET)

all NS

Rosiglitazonediabetes type 2, in patients inadequately controlled with insulin vs

all NS

Rosiglitazone vs placebo

all NS

Rosiglitazone vs placebo (add on insulin)

all NS