| PCI | coronary artery disease, in all type of patients | vs no PCI | all NS | | Endpoint | TE [95% CI] | p val | I2 | n | k | |
|---|
| Urgent revascularization | no data | | Definite or probable stent thrombosis | no data | | Repeat revascularization | 0.74 [0.48 1.13] | p=1.00 | 0 | 1186 | 2 | FAME, DEFER, | | cardiovascular events | 0.80 [0.58 1.11] | p=1.00 | 0 | 1186 | 2 | FAME, DEFER, | | Cardiovascular death | 0.51 [0.05 5.68] | p=1.00 | 0 | 181 | 1 | DEFER, | | myocardial infarction (fatal and non fatal) | 0.68 [0.42 1.10] | p=1.00 | 0 | 1186 | 2 | FAME, DEFER, | | stroke (fatal and non fatal) | no data | | All cause death | 0.58 [0.25 1.35] | p=1.00 | 0 | 1005 | 1 | FAME, |
| Trial | Studied treatment | Control | Patients |
|---|
| FAME, 2008 | FFR-guided PCI (PCI with implantation of drug-eluting stents guided by FFR measurements in addition to angiography | angiography-PCI (PCI with implantation of drug-eluting stents guided by angiography alone) | patients with multivessel coronary artery disease | | DEFER, 2001 | PCI | deferral (no PCI) | patients for whom PTCA was planned and who did not have documented ischemia and with fractional flow reserve >0.75 |
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