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Description Results

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All pathologies
venous thrombosis

all type of patients 122 - 64

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pathology

Benefit (demonstrated or suggested) and harm

venous thrombosis

All results are NS for efficacy

Trial

control

p<0.05

harm

NS

PREPIC, 1998

vs no filter

pulmonary embolims (symptomatic and asymptomatic) 0.22 [0.05; 0.93]

death 1.00 [0.29; 3.40]

major bleeding 1.50 [0.54; 4.14]

asymptomatic pulmonary embolism 0.00 [0.00; NaN]

symptomatic pulmonary embolism 0.40 [0.08; 2.04]

Trial

Treatments

Patients

Method

PREPIC, 1998

caval filter (n=200)

vs.

no filter (n=200)

2x2 factorial design also comparing LMWH vs unfractionated heparin

patients with documented proximal DVT or PE, and considered high risk for pulmonary embolism

open

Parallel groups

Sample size: 200/200

Primary endpoint: none

FU duration: 12 days and 2 years

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