| STOP-2 (ACEI vs felodipine or isradipine), 1999 | Enalapril or lisinopril
, enalapril 10 mg or lisinopril 10 mg daily
(n=2205) vs. felodipine 2.5 mg or isradipine 2-5 mg daily
(n=2196)
| patients aged 70-84 years with hypertension (blood pressure > or = 180 mm Hg systolic, > or = 105 mm Hg diastolic, or both)
| Open Parallel groups Sample size: 2205/2196 Primary endpoint: FU duration: 5·0 y
|
| STOP 2 (ACEI vs diurectic or beta-blocker), 1999 | enalapril 10 mg or lisinopril10 mg daily (n=2205) vs. conventional antihypertensive drugs (atenolol 50 mg, metoprolol 100 mg, pindolol 5 mg, or hydrochlorothiazide 25 mg plus amiloride 2·5 mg daily) (n=2213) | patients aged 70–84 years with hypertension (blood pressure >180 mm Hg systolic, >105 mm Hg diastolic, or both). | Open Parallel groups Sample size: 2205/2213 Primary endpoint: fatal stroke, fatal MI, other cardiovascular death FU duration: 5.0 y |
