new version V2017

Carfilzomib proteasome inhibitor

Kyprolis - carfilzomib      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

multiple myeloma

ECOG-ACRINcarfilzomibbortezomid - NCT01863550
CLARIONcarfilzomibbortezomid - NCT01818752
ASPIRE, 2014carfilzomib lenalidomide dexamethasonelenalidomide and dexamethasone alonerelapsed MMSuggestingNCT01080391
ENDEAVOR, 2016carfilzomibbortezomibrelapsed MM Risk of bias SuggestingNCT01568866
FOCUS, 2017carfilzomiblow-dose corticosteroids relapsed and refractory multiple myeloma (RRMM) Risk of bias NegativeNCT01302392