new version V2017

insulin sensitizer - biguanides

     

TrialStudied treatmentControl treatmentpatientsROBResultNCT

diabetes type 2

metformin
UKPDS (vs SU or INS)metforminSU/InsulinSuggesting
Teupe, 1991metforminplaceboNegative
Campbell, 1994metforminGlipizideNegative
Kooy (HOME), 2009metforminplacebo Low risk of bias Suggesting