Trial
|
Studied treatment |
Control |
Patients |
Size |
Study type
|
Results |
NCT |
Cardiovascular prevention - cholesterol lowering intervention in all chronical situations - cholesterol lowering intervention in patients with prior MI or with CHD - niacin in all type of patients - HDL increasing drugs in all type of patients |
Carlson (Stockholm), 1977 | clofibtate+niacin | placebo | secondary prevention | 555 (279/276) | Confirmatory - | | |
CLAS, 1987 | colestipol-niacin | placebo | Peripheral Arterial Disease | 188 (94/94) | Exploratory | | |
CLAS, 1987 | colestipol-niacin | placebo | secondary prevention | NA | Exploratory | | |
VA drugs, 1968 | niacin | control | | 220 (77/143) | Confirmatory | | |
ARBITER 6-HALTS (niacin vs ezetimibe), 2009 | niacin | ezetimibe | | 208 (97/111) | Exploratory | | NCT00397657 |
CDP niacin, 1975 | niacin | placebo | | 3908 (1119/2789) | Confirmatory | | |
AIM-HIGH, 2011 | niacin | placebo (on top statin) | | 3409 (1718/1691) | Confirmatory | | NCT00120289 |
HPS 2-Thrive | niacin | placebo (on top statin) | | 25673 (12838/12835) | Confirmatory | | NCT00461630 |
Oxford Niaspan Study, 2009 | niacin | placebo (on top statin) | | 71 (35/36) | Exploratory | | NCT00232531 |
ARBITER 2, 2009 | niacin | placebo (on top statin) | | 167 (87/80) | Exploratory | | |
HATS, 2001 | niacin | placebo (on top statin) | | 146 (73/73) | Confirmatory - | | |
UCSF SCOR, 1990 | niacin+colestipol | control | | 72 | Exploratory | | |
FATS, 1990 | niacin+colestipol | placebo | | 102 (48/54) | | | |
Guyton, 2008 | niacin+ezetimibe | simvastatin+ezetimibe | | NA | Exploratory | | |
Peripheral vascular diseases - cholesterol lowering intervention in all type of patients |
CLAS, 1987 | colestipol-niacin | placebo | Peripheral Arterial Disease | 188 (94/94) | Exploratory | | |
Post myocardial infarction - cholesterol lowering intervention in all type of patients |
Carlson (Stockholm), 1977 | clofibtate+niacin | placebo | secondary prevention | 555 (279/276) | Confirmatory - | | |