Niacin cholesterol lowering intervention

Lithium Nicotinate - Enduracin - Wampocap - Nicotinate - Nicolar - Nicocap - Nicobid - Nico400 - Nico 400 - Nico-400 - Nicamin - Induracin - 3 Pyridinecarboxylic Acid - 3-Pyridinecarboxylic Acid - Nicotinic Acid - Niacin



Trial Studied treatment Control Patients Size Study type Results NCT

Cardiovascular prevention - cholesterol lowering intervention in all chronical situations - cholesterol lowering intervention in patients with prior MI or with CHD - niacin in all type of patients - HDL increasing drugs in all type of patients

Carlson (Stockholm), 1977clofibtate+niacinplacebosecondary prevention555 (279/276) Confirmatory -
CLAS, 1987colestipol-niacinplaceboPeripheral Arterial Disease188 (94/94) Exploratory
CLAS, 1987colestipol-niacinplacebosecondary preventionNA Exploratory
VA drugs, 1968niacincontrol220 (77/143) Confirmatory
ARBITER 6-HALTS (niacin vs ezetimibe), 2009niacinezetimibe208 (97/111) Exploratory NCT00397657
CDP niacin, 1975niacinplacebo3908 (1119/2789) Confirmatory
AIM-HIGH, 2011niacinplacebo (on top statin)3409 (1718/1691) Confirmatory NCT00120289
HPS 2-Thriveniacinplacebo (on top statin)25673 (12838/12835) Confirmatory NCT00461630
Oxford Niaspan Study, 2009niacinplacebo (on top statin)71 (35/36) Exploratory NCT00232531
ARBITER 2, 2009niacinplacebo (on top statin)167 (87/80) Exploratory
HATS, 2001niacinplacebo (on top statin)146 (73/73) Confirmatory -
UCSF SCOR, 1990niacin+colestipolcontrol72 Exploratory
FATS, 1990niacin+colestipolplacebo102 (48/54)
Guyton, 2008niacin+ezetimibesimvastatin+ezetimibeNA Exploratory

Peripheral vascular diseases - cholesterol lowering intervention in all type of patients

CLAS, 1987colestipol-niacinplaceboPeripheral Arterial Disease188 (94/94) Exploratory

Post myocardial infarction - cholesterol lowering intervention in all type of patients

Carlson (Stockholm), 1977clofibtate+niacinplacebosecondary prevention555 (279/276) Confirmatory -