Lisinopril angiotensin-Converting Enzyme Inhibitors

MK-521 - Prinivil - Zestril - Lysinopril - Lisinopril

Trial	Studied treatment	Control	Patients	Size	Study type	Results	NCT
Acute myocardial infarction - angiotensin-Converting Enzyme Inhibitors in systematic early treatment (with or without sign of HF) - angiotensin-Converting Enzyme Inhibitors in patients with or without HF
GISSI 3, 1994	lisinopril	placebo		18895 (9435/9460)	Confirmatory -
Atrial fibrillation - prevention in patients without history of AF (primary prevention) - prevention in patient with history of atrial fibrillation
Van den Burg, 1995	lisinopril	placebo		18 (7/11)
GISSI-3 (AF ancillary study), 2003	lisinopril	placebo		17748 (8902/8846)
Diabetes type 2 - anti hypertensive agents in patients with hypertension - anti hypertensive agents in patients with or without hypertension - angiotensin renin system blockade in all type of patients
ALLHAT (lisi vs chlor, diabetic subgroup), 2002	lisinopril	chlorthalidone		6929 (2431/4498)	Exploratory
Heart failure - angiotensin-Converting Enzyme Inhibitors in all type of heart failure
Giles, 1990	lisinopril	control		193 (130/63)
Rucinska-c (lisinopril), 1000	lisinopril	control		58 (28/30)
Zwehl, 1990	lisinopril	control		275 (183/92)
ATLAS, 1999	lisinopril	lisinopril		3164 (1596/1568)	Confirmatory
Gilbert, 1993	lisinopril	placebo		28 (14/14)
International Study Group (Lewis), 1989	lisinopril	placebo		130 (87/43)	Exploratory
Hypertension - anti hypertensive agents in all type of patient - anti hypertensive agents in patients with additional risk factor - anti hypertensive agents in diabetic patients
ALLHAT (ACEI vs amlodipine), 2002	lisinopril	amlodipine		18102 (9054/9048)
ALLHAT (lisi vs chlor, diabetic subgroup), 2002	lisinopril	chlorthalidone		6929 (2431/4498)	Exploratory
ALLHAT (ACEI vs chlorthalidone), 2002	lisinopril	diuretics		24309 (9054/15255)	Confirmatory