Trial Studied treatment Control Patients Size Study type Results NCT

Diabetes type 2 - insulin secretagogues in all type of patients - insulin secretagogues - DPP-4 inhibitors in all types of patients - antidiabetic drugs in patients inadequately controlled on metformin - antidiabetic drugs in patients inadequately controlled on monotherapy - antidiabetic drugs in patients inadequately controlled with insulin - antidiabetic drugs in patients inadequately controlled on TZD

NCT00101673vildagliptinNA NCT00101673
Filozof, 2009vildagliptingliclazide (add on MET)1007 (513/494) NCT00102466
Goke, 2008vildagliptinmetforminNA
Schweizer, 2007vildagliptinmetformin780 (526/254) NCT00099866
Schweizer, 2009vildagliptinmetformin335 (169/166) NCT00246619
Bolli, 2008vildagliptinpioglitazone (add on MET)576 (295/281) NCT00237237
Mimori, 2006vildagliptinplaceboNA
Rosenstock, 2008vildagliptinplaceboNA NCT00237250
Scherbaum [2], 2008vildagliptinplacebo306 (156/150) NCT00101712
Kikuchi, 2010vildagliptinplacebo (add on glimepiride)202 (102/100) NCT00325117
Fonseca, 2007vildagliptinplacebo (add on insulin)296 (144/152) NCT00099931
Ahren, 2004vildagliptinplacebo (add on MET)107 (56/51)
Bosi, 2007vildagliptinplacebo (add on MET)367 (185/182) NCT00099892
Bosi, 2009vildagliptinplacebo (add on MET)1179 NCT00382096
Goodman, 2009vildagliptinplacebo (add on MET)247 (125/122) Exploratory
NCT00728351vildagliptinplacebo (add on MET)NA NCT00728351
NCT00822211vildagliptinplacebo (add on MET)NA NCT00822211
Garber, 2008vildagliptinplacebo (add on SU)515 NCT00099944
Rosenstock** (vilda + pio vs pio), 2007vildagliptinplacebo (add on TZD)NA NCT00101803
Garber, 2007vildagliptinplacebo (on top pioglitazone)463 NCT00099853
Rosenstock* (vilda vs rosi), 2007vildagliptinrosiglitazone786 (519/267) NCT00099918
Ferrannini, 2009vildagliptinSulfonylurea (add on to MET)2789 (1396/1393) Exploratory NCT00106340
GALIANT (Blonde), 2009vildagliptinTZD (add on MET)2478 (1653/825) NCT00396227
NCT00368134vildagliptinvogliboseNA NCT00368134
CLAF237A 23104vildagliptin + METMETNA NCT00396357
Pan, 2008vildagliptin monotherapyacarbose661 (441/220) NCT00110240
Foley, 2009vildagliptin monotherapygliclazideNA NCT00102388
Rosenstock** (vilda vs pio), 2007vildagliptin monotherapypioglitazoneNA NCT00101803
Dejager [1], 2007vildagliptin monotherapyplaceboNA NCT00099905
Foley, 2011vildagliptin monotherapyplacebo59 (29/30) NCT00260156
Kikuchi, 2009vildagliptin monotherapyplaceboNA
Pi-Sunyer, 2007vildagliptin monotherapyplaceboNA NCT00120536
Pratley, 2006vildagliptin monotherapyplacebo98 (70/28)
Ristic, 2005vildagliptin monotherapyplaceboNA



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