PTCA all percutaneous coronary intervention (PTCA, BMS, DES)



Trial Studied treatment Control Patients Size Study type Results NCT

Acute myocardial infarction - myocardial revascularization in all type of patients - PCI in all type of patients - Late revascularisation in late reperfusion - myocardial revascularization in >6h from onset of symptoms - myocardial revascularization in failed fibrinolysis (rescue revascularisation) - PCI in failed fibrinolysis (rescue PCI) - myocardial revascularization in patients in cardiogenic shock

ECSG, 1988immediate systematic ballon angioplastyteno immediate angioplasty367 (183/184) Exploratory
Belenkie, 1991immediate systematic ballon angioplastyteno immediate angioplasty89 (50/39) Exploratory
Ellis, 1994immediate systematic ballon angioplastyteno immediate angioplasty151 (78/73)
Erbel, 1989immediate systematic ballon angioplastyteno immediate angioplasty206 (103/103)
MERLIN (Sutton), 2004immediate systematic ballon angioplastyteno immediate angioplastyNA
SHOCK (Hochman), 1999immediate systematic ballon angioplastyteno immediate angioplasty302 (152/150) Confirmatory - NCT00000552
SWISS-SMASH, 1999immediate systematic ballon angioplastyteno immediate angioplasty55 (32/23) Exploratory
TAMI 1 pilot, 1987immediate systematic ballon angioplastyteno immediate angioplasty197 (99/98) Exploratory
TAMI-5 (Califf), 1991immediate systematic ballon angioplastyteno immediate angioplasty575 (287/288)
TIMI 2A, 1988immediate systematic ballon angioplastyteno immediate angioplasty389 (195/194) Exploratory
Topol, 1987immediate systematic ballon angioplastyteno immediate angioplasty28 (15/13) Exploratory
Horie et al, 1998late PTCAno PTCA83 (44/39)
TOAT, 2002late PTCAno PTCA66 (32/34)
TOMIIS, 1994late PTCAno PTCA44 (25/19)
DECOPI, 2004late PTCAno PTCA212 (109/103)
Silva et al, 2005late PTCAno PTCA36 (18/18)
OAT, 2006late PTCAno PTCA2166 (1082/1084)
TOSCA-2, 2006late PTCAno PTCA381 (195/186) NCT00025766
MAASTRICHT (Vermeer), 1999primary angioplastyimmediate thrombolysis150 (75/75)
PRAGUE-1, 2000primary angioplastyimmediate thrombolysis200 (101/99)
AIR-PAMI, 2002primary angioplastyimmediate thrombolysis137 (71/66)
CAPTIM, 2002primary angioplastyimmediate thrombolysis840 (421/419)
DANAMI-2, 2003primary angioplastyimmediate thrombolysis1129 (567/562)
PRAGUE-2, 2003primary angioplastyimmediate thrombolysis850 (429/421)
Belenkie, 1992rescue PTCAno rescue PTCA28 (16/12) Confirmatory -
REACT (rescue PCI), 2005rescue PTCAno rescue PTCA285 (144/141)
MERLIN, 2004rescue PTCAno rescue PTCA307 (153/154)
RESCUE II, 2000rescue PTCAno rescue PTCA29 (14/15)
RESCUE, 1994rescue PTCAno rescue PTCA151 (78/73)
SWIFT, 1991systematic ballon angioplastyno systematic angioplasty800 (397/403) Confirmatory -
SIAM, 1992systematic ballon angioplastyno systematic angioplasty324 (158/166) Exploratory
TAMI 6, 1992systematic ballon angioplastyno systematic angioplasty71 (34/37)
Barbash, 1990systematic ballon angioplastyno systematic angioplasty201 (97/104)
Guerci, 1987systematic ballon angioplastyno systematic angioplasty85 (42/43) Exploratory
TIMI 2, 1989systematic ballon angioplastyno systematic angioplasty3262 (1636/1626) Confirmatory -
TIMI II-A (defered)systematic ballon angioplastyno systematic angioplasty391 (194/197)
TOPS, 1992systematic ballon angioplastyno systematic angioplasty87 (42/45) Exploratory
Van den Brand, 1991systematic ballon angioplastyno systematic angioplasty217 (113/104) Exploratory
Vermeer, 1999systematic ballon angioplastyno systematic angioplastyNA

Coronary artery disease - myocardial revascularization in all type of patient - myocardial revascularization in multivessels disease - myocardial revascularization in single vessel disease

EAST, 1994balloon angioplastyCABG392 (198/194) NCT00000465
GABI, 1994balloon angioplastyCABG359 (182/177)
BARI, 1996balloon angioplastyCABG1829 (915/914) NCT00000462
RITA, 1993balloon angioplastyCABG1011 (510/501)
ERACI, 1992balloon angioplastyCABG127 (63/64)
MASS, 1995balloon angioplastyCABG142 (72/70)
Toulouse, 1992balloon angioplastyCABG152 (76/76)
Lausanne, 1994balloon angioplastyCABG134 (68/66)
CABRI, 1995balloon angioplastyCABG1054 (541/513)
RITA 2, 1997balloon angioplastymedical treatment1018 (504/514) Confirmatory -
ACME, 1992balloon angioplastymedical treatment212 (105/107) Confirmatory -
ACME 2 (Folland), 1997balloon angioplastymedical treatment101 (51/50) Confirmatory -
ACIP, 1997balloon angioplastymedical treatment558 (192/366) Exploratory
INSPIRE, 2006balloon angioplastymedical treatment205 (104/101) Confirmatory -
SWISSI II, 2007balloon angioplastymedical treatment201 (96/105) Exploratory NCT00387231
MASS, 1995balloon angioplastymedical treatment144 (72/72) Confirmatory -
Sievers, 1993balloon angioplastymedical treatment88 (44/44) Confirmatory -

Stable angina - myocardial revascularization in all type of patient - myocardial revascularization in multivessels disease - myocardial revascularization in single vessel disease

EAST, 1994balloon angioplastyCABG392 (198/194) NCT00000465
GABI, 1994balloon angioplastyCABG359 (182/177)
BARI, 1996balloon angioplastyCABG1829 (915/914) NCT00000462
RITA, 1993balloon angioplastyCABG1011 (510/501)
ERACI, 1992balloon angioplastyCABG127 (63/64)
MASS, 1995balloon angioplastyCABG142 (72/70)
Toulouse, 1992balloon angioplastyCABG152 (76/76)
Lausanne, 1994balloon angioplastyCABG134 (68/66)
CABRI, 1995balloon angioplastyCABG1054 (541/513)
RITA 2, 1997balloon angioplastymedical treatment1018 (504/514) Confirmatory -
ACME, 1992balloon angioplastymedical treatment212 (105/107) Confirmatory -
ACME 2 (Folland), 1997balloon angioplastymedical treatment101 (51/50) Confirmatory -
ACIP, 1997balloon angioplastymedical treatment558 (192/366) Exploratory
INSPIRE, 2006balloon angioplastymedical treatment205 (104/101) Confirmatory -
SWISSI II, 2007balloon angioplastymedical treatment201 (96/105) Exploratory NCT00387231
MASS, 1995balloon angioplastymedical treatment144 (72/72) Confirmatory -
Sievers, 1993balloon angioplastymedical treatment88 (44/44) Confirmatory -



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