Rosiglitazone antidiabetic drugs

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Trial Studied treatment Control Patients Size Study type Results NCT

Diabetes type 2 - insulin sensitizers - glitazones in all type of patients - insulin sensitizers - glitazones in patients with cardiovascular disease - insulin sensitizer in all type of patients - insulin sensitizer in patients with cardiovascular disease - prevention in all type of patients - prevention in people with impaired glucose tolerance - antidiabetic drugs in patients inadequately controlled with insulin - glucose lowering for cardiovascular prevention in all type of patients

AVM100264 rosiglitazone596 (294/302) Exploratory NCT00359112
BRL 49653C/185 rosiglitazone705 (563/142) Exploratory
SB-712753/007 rosiglitazone468 (314/154) Exploratory
SB-712753/009 rosiglitazone322 (162/160) Exploratory
Wang, 2005rosiglitazonecontrolNA Exploratory
APPROACH, 2008rosiglitazoneglipizide672 (333/339) Exploratory NCT00116831
49653/020 rosiglitazoneglyburide598 (391/207) Exploratory
49653/079 rosiglitazoneglyburide309 (203/106) Exploratory
49653/080 rosiglitazoneglyburide203 (104/99) Exploratory
49653/097 rosiglitazoneglyburide242 (122/120) Exploratory
49653/143 rosiglitazoneglyburide245 (121/124) Exploratory NCT00333723
49653/137 rosiglitazoneglyburide (add on MET)389 (204/185) Exploratory NCT00500955
49653/093 rosiglitazonemetformin322 (213/109) Exploratory
49653/094 rosiglitazonemetformin348 (232/116) Exploratory
49653/011 rosiglitazoneplacebo533 (357/176) Exploratory
DREAM rosiglitazone, 2006rosiglitazoneplacebo4999 (2365/2634) Confirmatory NCT00095654
49653/128 rosiglitazoneplacebo77 (39/38) Exploratory
49653/134 rosiglitazoneplacebo837 (561/276) Exploratory
49653/136 rosiglitazoneplacebo291 (148/143) Exploratory
49653/330 rosiglitazoneplacebo383 (1/382) Exploratory
49653/331 rosiglitazoneplacebo1031 (706/325) Exploratory
AVA100193 rosiglitazoneplacebo518 (394/124) Exploratory
BRL 49653/334 rosiglitazoneplacebo557 (278/279) Exploratory NCT00306644
49653/145 rosiglitazoneplacebo (add on glicazide)473 (231/242) Exploratory
49653/234 rosiglitazoneplacebo (add on glimepiride)177 (116/61) Exploratory
49653/135 rosiglitazoneplacebo (add on glipizide)227 (116/111) Exploratory
100684 rosiglitazoneplacebo (add on glyburide)90 (43/47) Exploratory NCT01045590
49653/127 rosiglitazoneplacebo (add on glyburide)114 (56/58) Exploratory
49653/162 rosiglitazoneplacebo (add on glyburide)340 (168/172) Exploratory
49653/085 rosiglitazoneplacebo (add on insulin)277 (138/139) Exploratory
49653/095 rosiglitazoneplacebo (add on insulin)292 (196/96) Exploratory
BRL 49653/347 rosiglitazoneplacebo (add on insulin)630 (418/212) Exploratory NCT00054782
49653/284 rosiglitazoneplacebo (add on MET)766 (382/384) Exploratory NCT00501020
712753/008 rosiglitazoneplacebo (add on MET)419 (284/135) Exploratory NCT00241605
SB-712753/002 rosiglitazoneplacebo (add on MET)568 (288/280) Exploratory
SB-712753/003 rosiglitazoneplacebo (add on MET)526 (254/272) Exploratory
49653/015 rosiglitazoneplacebo (add on SU)593 (395/198) Exploratory
49653/125 rosiglitazoneplacebo (add on SU)348 (175/173) Exploratory NCT00422955
49653/132 rosiglitazoneplacebo (add on SU)554 (442/112) Exploratory
49653/147 rosiglitazoneplacebo (add on SU)177 (89/88) Exploratory
ADOPT, 2006rosiglitazonestandard glucose-lowering drugs4351 (1456/2895) Exploratory NCT00279045
RECORD, 2009rosiglitazonestandard glucose-lowering drugs4447 (2220/2227) Confirmatory - NCT00379769
49653/211 rosiglitazoneusual care224 (110/114) Exploratory

Impaired fasting glucose - prevention in all type of patients

DREAM rosiglitazone, 2006rosiglitazoneplacebo4999 (2365/2634) Confirmatory NCT00095654

Percutaneous coronary intervention - restenosis prevention in all type of patients

PROVIDENCE ongoing rosiglitazoneplaceboNA Exploratory NCT00116792



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