PCI all percutaneous coronary intervention (PTCA, BMS, DES)



Trial Studied treatment Control Patients Size Study type Results NCT

Acute myocardial infarction - myocardial revascularization in all type of patients - PCI in all type of patients - myocardial revascularization in patient ineligible for thrombolysis - PCI in patient ineligible for thrombolysis - PCI in Elderly patients - myocardial revascularization in Elderly patients

C-PORT, 2002primary PCIaccelerated t-PA451 (225/226)
senior PAMI, 2005primary PCIThrombolysis481 (252/229) Confirmatory - NCT00136929
STAT, 2001primary stentingaccelerated t-PA123 (62/61)
Zwolle 5 (Suryapranata), 1998primary stentingballoon angioplasty227 (112/115)
FRESCO, 1998primary stentingballoon angioplasty150 (75/75)
GRAMI (Rodriguez), 1998primary stentingballoon angioplasty104 (52/52)
PASTA (Saito), 1999primary stentingballoon angioplasty137 (67/70)
stent-PAMI (Grines), 1999primary stentingballoon angioplasty900 (452/448)
STENTIM-2 (Maillard), 2000primary stentingballoon angioplasty211 (101/110)
PSSAAMI (Scheller), 2001primary stentingballoon angioplasty88 (44/44)
Jaksch, 1998primary stentingballoon angioplasty462 (231/231)
PRISAM (Kawashima), 1999primary stentingballoon angioplasty222 (110/112)
CADILLAC (no abciximab), 2002primary stentingballoon angioplasty1030 (512/518)
CADILLAC abciximab., 2002primary stentingballoon angioplasty1052 (524/528)
ZWOLLE 6, 2005primary stentingballoon angioplasty1548 (785/763)
STOPAMI 3, 2004primary stentingballoon angioplasty611 (305/306)
STOPAMI 2, 2002primary stentingimmediate thrombolysis162 (81/81)
CAPITAL AMI, 2005systematic PCI (+stent)no systematic PCI170 (86/84)
GRACIA-1, 2004systematic PCI (+stent)no systematic PCI499 (248/251) Confirmatory -
PRAGUE, 2000systematic PCI (+stent)no systematic PCI199 (100/99)
SIAM III, 2002systematic PCI (+stent)no systematic PCI163 (82/81)
WEST, 2006systematic PCI (+stent)no systematic PCI204 (104/100)

Coronary artery disease - myocardial revascularization in all type of patient - Drug eluting stent in all type of patients - Drug eluting stent in unparticular patients - fractional-flow-reserve-guided PCI in all type of patients - myocardial revascularization in multivessels disease

FAME, 2008FFR-guided PCIno PCI1005 (509/496) NCT00267774
DEFER, 2001FFR-guided PCIno PCI181 (90/91)
AWESOME, 2001PCICABG454 (222/232) Confirmatory -
COMBAT ongoing PCICABGNA
Korean Randomized Study ongoing PCICABGNA
REVASCULARIZE ongoing PCICABGNA
TIME, 2001PCI with or without stentmedical treatmentNA Confirmatory -
AVERT, 1995PCI with or without stentmedical treatment341 (177/164) Confirmatory -
Dakik, 1998PCI with or without stentmedical treatment41 (19/22) Confirmatory -
MASS II, 2007PCI with or without stentmedical treatment408 (205/203) Confirmatory -
COURAGE, 2007PCI with or without stentmedical treatment2287 (1149/1138) Confirmatory - NCT00007657
ALKK, 2003PCI with or without stentmedical treatment300 (149/151) Confirmatory -
Hambrecht, 2004PCI with or without stentmedical treatment101 (50/51) Confirmatory -
Bech, 2001PCI with or without stentmedical treatment181 (90/91) Confirmatory -

Stable angina - myocardial revascularization in all type of patient - myocardial revascularization in multivessels disease - myocardial revascularization in single vessel disease

FAME, 2008FFR-guided PCIno PCI1005 (509/496) NCT00267774
DEFER, 2001FFR-guided PCIno PCI181 (90/91)
AWESOME, 2001PCICABG454 (222/232) Confirmatory -
TIME, 2001PCI with or without stentmedical treatmentNA Confirmatory -
AVERT, 1995PCI with or without stentmedical treatment341 (177/164) Confirmatory -
Dakik, 1998PCI with or without stentmedical treatment41 (19/22) Confirmatory -
MASS II, 2007PCI with or without stentmedical treatment408 (205/203) Confirmatory -
COURAGE, 2007PCI with or without stentmedical treatment2287 (1149/1138) Confirmatory - NCT00007657
ALKK, 2003PCI with or without stentmedical treatment300 (149/151) Confirmatory -
Hambrecht, 2004PCI with or without stentmedical treatment101 (50/51) Confirmatory -
Bech, 2001PCI with or without stentmedical treatment181 (90/91) Confirmatory -



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