Fondaparinux antithrombotics

Arixtra - Quixidar



Trial Studied treatment Control Patients Size Study type Results NCT

Acute coronary syndrome - antithrombotics in all type of patients - antithrombotics in PCI sub group

OASIS 5, 2006fondaparinuxenoxaparin20078 (10057/10021) NCT00139815
PENTUA, 2004fondaparinuxenoxaparin1138 (908/230)

Acute myocardial infarction - antithrombotics in all type of patients

MICHELANGELO OASIS-6, 2006fondaparinuxplacebo12092 (6036/6056) Confirmatory NCT00064428

Percutaneous coronary intervention - antithrombotics in all type of patients - anticoagulant in all type of patients

SWITCH III ongoing fondaparinuxunfractionated heparin or bivalirudinNA NCT00464087

Pulmonary embolism - antithrombotics in all type of patients

MATISSE PE, 2003fondaparinuxheparin2213 (1103/1110) Confirmatory -

Superficial thrombophlebitis - antithrombotics in superficial thrombophlebitis of the leg

CALISTO, 2010fondaparinuxplacebo3002 (1502/1500) Confirmatory NCT00443053

Thrombosis prevention - antithrombotics in orthopedic surgery - antithrombotics in elective major knee surgery - pentasaccharide in orthopedic surgery - pentasaccharide in all type of patients - antithrombotics in hip Fracture - antithrombotics in elective hip replacement - antithrombotics in medical patients - pentasaccharide in medical patients - antithrombotics in abdominal surgery - pentasaccharide in abdominal surgery - antithrombotics in patients with immobilization of the lower extremities

NCT00333021 ongoing fondaparinuxcontrolNA NCT00333021
NCT00320398 ongoing fondaparinuxcontrolNA NCT00320398
BRiEFfondaparinuxenoxaparinmedical patientsNA NCT00521885
L8541fondaparinuxenoxaparinorthopaedic surgery237 (119/118) Confirmatory
L8635fondaparinuxenoxaparinknee surgery51 (28/23) Exploratory
PENTAMAKS (Bauer), 2001fondaparinuxenoxaparinknee surgery1034 (517/517) Confirmatory
PENTHIFRA (Eriksson), 2001fondaparinuxenoxaparinhip surgery1671 (831/840) Confirmatory
EPHESUS (Lassen), 2002fondaparinuxenoxaparinhip surgery2309 (1155/1154)
PENTATHLON (Turpie), 2002fondaparinuxenoxaparinhip surgery2275 (1138/1137) Confirmatory
PEGASUS, 2005fondaparinuxenoxaparinabdominal surgery2927 (1465/1462) Confirmatory
Turpie, 2001fondaparinuxenoxaparinhip surgery933 (673/260) Exploratory
FONDACAST ongoing fondaparinuxnadroparinNA NCT00843492
PROTECT (fundaparinux) ongoing fondaparinuxno treatmentNA NCT00881088
DRI4757fondaparinuxplaceboknee surgery432 (345/87) Exploratory
ARTEMIS (Cohen), 2006fondaparinuxplacebomedical patients839 (425/414)
APOLLO (Turpie), 2007fondaparinuxplacebo (on top intermittent pneumatic comp.)abdominal surgery1309 (650/659) Confirmatory

Venous thrombosis - antithrombotics in all type of patients

MATISSE, 2004fondaparinuxenoxaparin2205 (1098/1107) Confirmatory
MATISSE PE, 2003fondaparinuxheparin2213 (1103/1110) Confirmatory -



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