Sitagliptin antidiabetic drugs

MK-0431 - MK0431 - MK 0431 - Januvia - sitagliptin phosphate - sitagliptin



Trial Studied treatment Control Patients Size Study type Results NCT

Diabetes type 2 - insulin secretagogues in all type of patients - insulin secretagogues - DPP-4 inhibitors in all types of patients - antidiabetic drugs in patients inadequately controlled on metformin - antidiabetic drugs in patients inadequately controlled on monotherapy - antidiabetic drugs in patients with insufficient glycaemic control with bitherapy - glucose lowering for cardiovascular prevention in all type of patients

Stafford , 2011sitagliptinNA NCT00451113
Reasner, 2011sitagliptincontrol (add on MET)NA NCT00482729)
Arechavaleta, 2011sitagliptinglimepiride (add on MET)1035 (516/519) NCT00701090
Goldstein (sit vs met), 2007sitagliptinmetforminNA
Goldstein (sit+met vs met), 2007sitagliptinmetforminNA
Pérez-Monteverde, 2011sitagliptinpioglitazoneNA NCT00541450
Goldstein, 2007sitagliptinplaceboNA NCT00103857
Hanefeld, 2007sitagliptinplaceboNA
TECOS, 2015sitagliptinplacebo14671 (7332/7339) Exploratory NCT00790205
Vilsbøll, 2010sitagliptinplacebo (add on insulin+/-MET)641 (322/319) NCT00395343
Charbonnel, 2006sitagliptinplacebo (add on MET)NA NCT0086515
Nauck, 2007sitagliptinplacebo (add on MET)NA NCT00094770
raz, 2008sitagliptinplacebo (add on MET)NA NCT00337610
Scott** (sit vs pbo on top met), 2007sitagliptinplacebo (add on MET)NA
Rosenstock , 2006sitagliptinplacebo (add on PIO)NA NCT00086502
Rosenstock (sit on top pio vs pbo), 2006sitagliptinplacebo (on top PIO)NA NCT00086502
Hermansen, 2007sitagliptinplacebo (on-top glimepiride+/- metformine)NA
Rigby , 2010sitagliptinrosiglitazone (add on MET)NA
Al Sifri, 2011sitagliptinSulphonylurea (on top MET)1021 (507/514)
Scott* (sit vs glipi), 2007sitagliptin 50mg bid monotherapyglipizideNA
Scott* (sit vs pbo), 2007sitagliptin 50mg bid monotherapyplaceboNA
Aschner, 2010sitagliptin monotherapymetformin1050 (528/522) NCT00449930
Aschner, 2006sitagliptin monotherapyplaceboNA NCT00087516
Barzilai, 2011sitagliptin monotherapyplaceboNA NCT00305604
Chan, 2008sitagliptin monotherapyplacebo91 (65/26)
Mohan , 2009sitagliptin monotherapyplaceboNA
Nonaka, 2008sitagliptin monotherapyplaceboNA NCT00371007
Raz, 2006sitagliptin monotherapyplaceboNA
Iwamoto , 2010sitagliptin monotherapyvogliboseNA
Derosa , 2010sitagliptin+piometformin+pioNA



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