Streptokinase fibrinolysis



Trial Studied treatment Control Patients Size Study type Results NCT

Acute myocardial infarction - myocardial revascularization in all type of patients - fibrinolysis in all type of patients - myocardial revascularization in facilated PCI - Late revascularisation in late reperfusion - myocardial revascularization in >6h from onset of symptoms

EMERAS (7-12h), 1993streptokinaseplacebo4534 (2257/2277)
EMERAS (all delay), 1993streptokinaseplacebo4534 (2257/2277)
GISSI I, 1986streptokinaseplacebo11712 (5860/5852)
ISAM, 1986streptokinaseplacebo1741 (859/882)
ISIS 2 pilot, 1987streptokinaseplaceboNA
ISIS-2 (SK), 1988streptokinaseplacebo17187 (8592/8595)
Western Washington Intravenous Trial, 1988streptokinaseplacebo368 (191/177) NCT00000507
SAMI (O’Neill), 1992streptokinaseprimary intervention122 (59/63)
PRAGUE (Widimisky), 2000streptokinaseprimary intervention201 (100/101)
GUSTO tPA-SK Hiv, 1993t-PA + streptokinasestreptokinase30625 (10374/20251)

Pulmonary embolism - fibrinolysis in all type of patients

Tibbutt, 1974streptokinaseno fibrinolysis30 (17/13) Exploratory
Ly, 1978streptokinaseno fibrinolysis25 (14/11) Exploratory
Jerjes-Sanchez, 1995streptokinaseno fibrinolysis48 (43/5) Exploratory

Venous thrombosis - fibrinolysis in all type of patients

Arneson, 1978streptokinaseno fibrinolysis43
Common, 1976streptokinaseno fibrinolysis50
Elsharawy, 2002streptokinaseno fibrinolysis35
Schulman, 1986streptokinaseno fibrinolysis38
Tsapogas, 1973streptokinaseno fibrinolysis34
Kakkar (streptokinase), 1969streptokinaseno fibrinolysisNA
Schweizer (systemic SK), 2000streptokinaseno fibrinolysisNA



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