trial summary

Diabetic patients : 1 trials - Cocozza

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
unstable angina	no data
stable angina	no data
Peripheral vascular events	no data
cardiovascular events	0.08 [0.00 1.45]	p=1.00	0	50	1	Cocozza,
Cardiovascular death	0.33 [0.01 8.60]	p=1.00	0	50	1	Cocozza,
myocardial infarction (fatal and non fatal)	no data
stroke (fatal and non fatal)	no data
Coronary event	no data
Coronary death	no data
Fatal MI	no data
Non fatal MI	no data
Revascularization	no data
All cause death	no data
Fatal stroke	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

Secondary prevention in patients with intermittent claudication: 3 trials - ADEP - Neirotti - Coto

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
Amputation	0.83 [0.25 2.76]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
myocardial infarction (fatal and non fatal)	0.52 [0.04 6.74]	p=1.00	0	60	2	Neirotti,Coto,
Vascular death	0.59 [0.23 1.50]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
Fatal MI	1.00 [0.06 16.87]	p=1.00	0	60	2	Neirotti,Coto,
Non fatal MI	0.87 [0.46 1.64]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
Vascular events	0.78 [0.49 1.23]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
All cause death	0.91 [0.50 1.67]	p=1.00	0	2344	2	ADEP,Coto,
Fatal stroke	1.00 [0.06 16.87]	p=1.00	0	60	2	Neirotti,Coto,
Non fatal stroke	0.92 [0.40 2.09]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
Non cerebral major bleeding	no data
Fatal bleeding	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

All type of patients: 1 trials - Cocozza

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
unstable angina	no data
stable angina	no data
Peripheral vascular events	no data
cardiovascular events	0.08 [0.00 1.45]	p=1.00	0	50	1	Cocozza,
Cardiovascular death	0.33 [0.01 8.60]	p=1.00	0	50	1	Cocozza,
myocardial infarction (fatal and non fatal)	no data
stroke (fatal and non fatal)	no data
Coronary event	no data
Coronary death	no data
Fatal MI	no data
Non fatal MI	no data
Revascularization	no data
All cause death	no data
Fatal stroke	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

Patients without cardiovascular disease: 1 trials - Cocozza

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
unstable angina	no data
stable angina	no data
Peripheral vascular events	no data
cardiovascular events	0.08 [0.00 1.45]	p=1.00	0	50	1	Cocozza,
Cardiovascular death	0.33 [0.01 8.60]	p=1.00	0	50	1	Cocozza,
myocardial infarction (fatal and non fatal)	no data
stroke (fatal and non fatal)	no data
Coronary event	no data
Coronary death	no data
Fatal MI	no data
Non fatal MI	no data
Revascularization	no data
All cause death	no data
Fatal stroke	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

All type of patient: 3 trials - ADEP - Neirotti - Coto

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
Amputation	0.83 [0.25 2.76]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
myocardial infarction (fatal and non fatal)	0.52 [0.04 6.74]	p=1.00	0	60	2	Neirotti,Coto,
Vascular death	0.59 [0.23 1.50]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
Fatal MI	1.00 [0.06 16.87]	p=1.00	0	60	2	Neirotti,Coto,
Non fatal MI	0.87 [0.46 1.64]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
Vascular events	0.78 [0.49 1.23]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
All cause death	0.91 [0.50 1.67]	p=1.00	0	2344	2	ADEP,Coto,
Fatal stroke	1.00 [0.06 16.87]	p=1.00	0	60	2	Neirotti,Coto,
Non fatal stroke	0.92 [0.40 2.09]	p=1.00	0	2364	3	ADEP,Neirotti,Coto,
Non cerebral major bleeding	no data
Fatal bleeding	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients