Nebivolol vs placebo | No demonstrated result suggested Sudden death by 37% (not demonstrated) | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
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Death from any cause or hospitalization for any reason | 0.88 [0.73 1.05] | p=1.00 | 0 | 2128 | 1 | SENIORS, | Sudden death | 0.63 [0.42 0.92] | p=0.04 | 0 | 2128 | 1 | SENIORS, | NYHA class improvement | 1.00 [0.02 60.00] | p=1.00 | 0 | 12 | 1 | Lechat, | cardiovascular events | no data | Cardiovascular death | 0.84 [0.65 1.09] | p=1.00 | 0 | 2128 | 1 | SENIORS, | Coronary event | no data | Coronary death | no data | hospitalisation for heart failure | 1.09 [0.06 19.07] | p=1.00 | 0 | 36 | 2 | Lechat,Wisenbaugh, | All cause death | 0.88 [0.70 1.10] | p=1.00 | 0 | 2164 | 3 | Lechat,Wisenbaugh,SENIORS, | TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |