Ribociclib CDK (cyclin-dependent kinase) inhibitor

LEE011 - ribociclib

Advanced breast cancer (metastatic)

All type of patients:  3 trials  - MONALEESA-3 - MONALEESA-2 - MONALEESA-7

ribociclib (LEE011) + letrozole vs letrozole alone

progression or death (progression free survival PFS) by 44% (fully demonstrated)

ribociclib (LEE011) + nsAI/TAM gos vs nsAI/TAM + gos

No demonstrated result

ribociclib (LEE011)+ fulvestrant vs fulvestrant alone

No demonstrated result

See more clinical conditions

HR+ HER2-:  3 trials  - MONALEESA-3 - MONALEESA-2 - MONALEESA-7

ribociclib (LEE011) + letrozole vs letrozole alone

progression or death (progression free survival PFS) by 44% (fully demonstrated)

ribociclib (LEE011) + nsAI/TAM gos vs nsAI/TAM + gos

No demonstrated result

ribociclib (LEE011)+ fulvestrant vs fulvestrant alone

No demonstrated result