Intensive blood pressure lowering strategies intensive blood pressure control

intensified blood-pressure control - strict blood pressure control - low target blood pressure - tighter control of blood pressure - intensive treatment

Diabetes type 2

Patients with hypertension:  2 trials  - ABCD target (H) - ABCD target (N)

more intensive blood pressure lowering strategie vs less intensive blood pressure lowering strategie

No demonstrated result

suggested non cardiovascular death by 59% (not demonstrated)

Hypertension

All type of patients:  17 trials  - MDRD - HOT - ABCD target (H) - AASK - REIN-2 - ABCD target (N) - Toto - ACCORD blood pressure - Cardio-Sis - SPRINT - UKPDS-HDS - JATOS - VANLISH - HOMED-BP - SPS3 - Wei - PAST-BP

more intensive blood pressure lowering strategie vs less intensive blood pressure lowering strategie

No demonstrated result

suggested cardiovascular events by 17% (not demonstrated)

suggested Cardiovascular death by 16% (not demonstrated)

suggested myocardial infarction (fatal and non fatal) by 14% (not demonstrated)

suggested stroke (fatal and non fatal) by 17% (not demonstrated)

suggested Serious adverse event by 104% (not demonstrated)

suggested Heart failure by 27% (not demonstrated)

suggested left ventricular hypertrophy by 33% (not demonstrated)

suggested End stage renal disease by 15% (not demonstrated)

suggested All cause death by 11% (not demonstrated)

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Diabetic patients :  3 trials  - ABCD target (H) - ABCD target (N) - ACCORD blood pressure

more intensive blood pressure lowering strategie vs less intensive blood pressure lowering strategie

No demonstrated result

suggested stroke (fatal and non fatal) by 41% (not demonstrated)

suggested Serious adverse event by 158% (not demonstrated)

suggested non cardiovascular death by 59% (not demonstrated)

Non diabetic patients:  6 trials  - MDRD - HOT - REIN-2 - Toto - Cardio-Sis - SPRINT

more intensive blood pressure lowering strategie vs less intensive blood pressure lowering strategie

No demonstrated result

suggested cardiovascular events by 17% (not demonstrated)

suggested Heart failure by 36% (not demonstrated)

suggested left ventricular hypertrophy by 33% (not demonstrated)

suggested End stage renal disease by 19% (not demonstrated)

Patients with chronic kidney disease :  4 trials  - MDRD - AASK - REIN-2 - Toto

more intensive blood pressure lowering strategie vs less intensive blood pressure lowering strategie

No demonstrated result

suggested End stage renal disease by 17% (not demonstrated)