All type of patients: 6 trials - PEARL - PALOMA-4 - PALOMA-2 - PALOMA 3 - PENELOPE-B - PALOMA 1/TRIO-18
| palbociclib vs placebo | No demonstrated result | |
| palbociclib + letrozole vs letrozole alone | No demonstrated result | |
| palbociclib + exemestane vs capecitabine | No demonstrated result | |
| palbociclib + fulvestrant vs fulvestrant alone | progression or death (progression free survival PFS) by 58% (fully demonstrated) | |
| palbociclib + letrozole vs letrozole alone | progression or death (progression free survival PFS) by 44% (fully demonstrated) |
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