lorcaserin vs placebo | No demonstrated result suggested weight loss equal to or greater than 5 percent by 111% (not demonstrated) suggested weight loss equal to or greater than 10 percent by 163% (not demonstrated) | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
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weight loss equal to or greater than 5 percent | 2.11 [1.89 2.34] | p=0.04 | 0 | 6635 | 3 | BLOSSOM (10mg bid),BLOOM,BLOOM-DM (10mg bid), | weight loss equal to or greater than 10 percent | 2.63 [2.27 3.05] | p=0.04 | 0 | 6635 | 3 | BLOSSOM (10mg bid),BLOOM,BLOOM-DM (10mg bid), | cardiovascular events | no data | TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |