Coronary Artery Bypass Surgery trial summary

Coronary artery disease

All type of patient: 12 trials - MASS II - Allen - Loubani - Zhao - BARI 2D - VA - ECSS (European) - CASS - Texas - Oregon - New zealand 1 - STICH (ventricular reconstruction)

CABG vs medical treatment

No demonstrated result

suggested 5-year death by 35% (not demonstrated)

suggested 7-year death by 26% (not demonstrated)

Endpoint	TE [95% CI]	p val	n	k	trials
5-year death	0.65 [0.52 0.81]	p=0.04	2955	7	MASS II,VA,ECSS (European),CASS,Texas,Oregon,New zealand 1,
7-year death	0.74 [0.61 0.91]	p=0.04	2549	6	VA,ECSS (European),CASS,Texas,Oregon,New zealand 1,
10-year death	0.87 [0.73 1.04]	p=1.00	2549	6	VA,ECSS (European),CASS,Texas,Oregon,New zealand 1,

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

CABG or PCI vs medical treatment

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
5-year death	0.98 [0.77 1.24]	p=1.00	0	2368	1	BARI 2D,
7-year death	no data
10-year death	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

CABG+surgical ventricular reconstruction vs CABG

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
death or hospitalization for cardiac causes	0.99 [0.77 1.27]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
hospitalisation for cardiovascular causes	0.96 [0.75 1.24]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
death or vein graft failure	no data
myocardial infarction (fatal and non fatal)	0.91 [0.49 1.68]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
stroke (fatal and non fatal)	0.74 [0.42 1.29]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
Long term death	no data
All cause death	0.97 [0.74 1.29]	p=1.00	0	1000	1	STICH (ventricular reconstruction),

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

TMR+CABG vs CABG

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
cardiac event (fatal and non fatal )	no data
Angina relief	no data
Angina class improvement + death	no data
Long term death	no data
All cause death	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

See more clinical conditions

All type of patients: 3 trials - Allen - Loubani - Zhao

TMR+CABG vs CABG

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
cardiac event (fatal and non fatal )	no data
Angina relief	no data
Angina class improvement + death	no data
Long term death	no data
All cause death	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

Diabetic patients : 1 trials - BARI 2D

CABG or PCI vs medical treatment

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
5-year death	0.98 [0.77 1.24]	p=1.00	0	2368	1	BARI 2D,
7-year death	no data
10-year death	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

Stable angina

All type of patient: 12 trials - MASS II - Allen - Loubani - Zhao - BARI 2D - VA - ECSS (European) - CASS - Texas - Oregon - New zealand 1 - STICH (ventricular reconstruction)

CABG vs medical treatment

No demonstrated result

suggested 5-year death by 35% (not demonstrated)

suggested 7-year death by 26% (not demonstrated)

Endpoint	TE [95% CI]	p val	n	k	trials
5-year death	0.65 [0.52 0.81]	p=0.04	2955	7	MASS II,VA,ECSS (European),CASS,Texas,Oregon,New zealand 1,
7-year death	0.74 [0.61 0.91]	p=0.04	2549	6	VA,ECSS (European),CASS,Texas,Oregon,New zealand 1,
10-year death	0.87 [0.73 1.04]	p=1.00	2549	6	VA,ECSS (European),CASS,Texas,Oregon,New zealand 1,

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

CABG or PCI vs medical treatment

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
5-year death	0.98 [0.77 1.24]	p=1.00	0	2368	1	BARI 2D,
7-year death	no data
10-year death	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

CABG+surgical ventricular reconstruction vs CABG

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
death or hospitalization for cardiac causes	0.99 [0.77 1.27]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
hospitalisation for cardiovascular causes	0.96 [0.75 1.24]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
death or vein graft failure	no data
myocardial infarction (fatal and non fatal)	0.91 [0.49 1.68]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
stroke (fatal and non fatal)	0.74 [0.42 1.29]	p=1.00	0	1000	1	STICH (ventricular reconstruction),
Long term death	no data
All cause death	0.97 [0.74 1.29]	p=1.00	0	1000	1	STICH (ventricular reconstruction),

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

TMR+CABG vs CABG

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
cardiac event (fatal and non fatal )	no data
Angina relief	no data
Angina class improvement + death	no data
Long term death	no data
All cause death	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

See more clinical conditions

Diabetic patients : 1 trials - BARI 2D

CABG or PCI vs medical treatment

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
5-year death	0.98 [0.77 1.24]	p=1.00	0	2368	1	BARI 2D,
7-year death	no data
10-year death	no data

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

Coronary Artery Bypass Surgery myocardial revascularization

CABG - Coronary Artery Bypass Grafting - Aortocoronary Bypasses - Aortocoronary Bypass - Coronary Artery Bypass Surgery - Coronary Artery Bypasses - Coronary Artery Bypass

Coronary artery disease

Stable angina