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Obesity and overweight

All type of patients: 4 trials - McMahon - McMahon - Smith - SCOUT

Sibutramine vs placebo

No demonstrated result

suggested cardiovascular events by 16% (not demonstrated)

Endpoint	TE [95% CI]	p val	I2	n	k	trials
weight loss equal to or greater than 5 percent	no data
weight loss equal to or greater than 10 percent	no data
cardiovascular events	1.16 [1.03 1.31]	p=0.04	0	9804	1	SCOUT,

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

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