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Betrixaban anticoagulant

PRT054021

Atrial fibrillation

Thrombosis prevention

Medical patients: 1 trials - APEX

betrixaban vs enoxaparin

No demonstrated result

Endpoint	TE [95% CI]	p val	I2	n	k	trials
Symptomatic deep-vein thrombosis	0.81 [0.65 1.00]	p=1.00	0	7513	1	APEX,
Symptomatic pulmonary embolism	0.79 [0.63 1.00]	p=1.00	0	7513	1	APEX,
Deep vein thrombosis	no data
proximal deep-vein thrombosis	0.79 [0.63 1.00]	p=1.00	0	7513	1	APEX,
Venous thromboembolism or death	0.81 [0.64 1.03]	p=1.00	0	3870	1	APEX,
asymptomatic DVT	no data
pulmonary embolism (symptomatic and asymptomatic)	no data
fatal pulmonary embolism	no data
Venous thromboembolism	0.81 [0.64 1.03]	p=1.00	0	3870	1	APEX,
All cause death	no data
Major bleeding	1.19 [0.67 2.12]	p=1.00	0	7513	1	APEX,
net benefit	0.83 [0.66 1.04]	p=1.00	0	3870	1	APEX,

TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients

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