ketanserine vs placebo | No demonstrated result | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
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Amputation | 0.60 [0.33 1.09] | p=1.00 | 0 | 3899 | 1 | PACK, | myocardial infarction (fatal and non fatal) | 0.90 [0.56 1.45] | p=1.00 | 0 | 4064 | 2 | PACK,Thulesius, | Vascular death | 1.26 [0.91 1.76] | p=1.00 | 0 | 4099 | 3 | PACK,Walden,Thulesius, | Fatal MI | 0.55 [0.05 6.75] | p=1.00 | 0 | 200 | 2 | Walden,Thulesius, | Non fatal MI | 0.36 [0.01 9.04] | p=1.00 | 0 | 165 | 1 | Thulesius, | Vascular events | no data | All cause death | 1.13 [0.85 1.51] | p=1.00 | 0 | 4099 | 3 | PACK,Walden,Thulesius, | Fatal stroke | 0.55 [0.05 6.75] | p=1.00 | 0 | 200 | 2 | Walden,Thulesius, | Non fatal stroke | 2.05 [0.17 25.35] | p=1.00 | 0 | 200 | 2 | Walden,Thulesius, | Non cerebral major bleeding | no data | Fatal bleeding | 0.36 [0.01 9.04] | p=1.00 | 0 | 165 | 1 | Thulesius, | TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |