| biolimus eluting stent vs sirolimus eluting stent | No demonstrated result | | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
|---|
| 2 yr Death (all cause) | no data | | myocardial infarction (fatal and non fatal) | 1.25 [0.81 1.92] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | 4 yr mortality from all causes | no data | | cardiac death | 0.66 [0.33 1.31] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | 4 yr MI | no data | | 4 yr death or MI | no data | | MACE | 0.92 [0.67 1.27] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | 2 yr MACE | no data | | target-vessel revascularization | 0.80 [0.52 1.24] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | 2 yr TLR | no data | | 4 yr TLR | no data | | target lesion revascularisation | 0.87 [0.56 1.37] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | CABG | 0.50 [0.20 1.23] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | in-lesion binary restenosis | no data | | angiographic restenosis | 0.64 [0.31 1.30] | p=1.00 | 0 | 484 | 1 | LEADERS, | | All cause death | 0.91 [0.51 1.63] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | Stent thrombosis (any, end of follow up) | 1.15 [0.62 2.14] | p=1.00 | 0 | 1707 | 1 | LEADERS, | | 4y stent thrombosis (ARC) | no data | | 4 yr stent thrombosis | no data | | Acute stent thrombosis (<=24h) | no data | | sub acute stent thrombosis (1-30 days) | no data | | late stent thrombosis (31days - 1year) | 0.99 [0.25 3.98] | p=1.00 | 0 | 1707 | 1 | LEADERS, |
TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |
