All type of patients: 13 trials - A4 (Jais) - Wazni - RESOLVE-AF - MANTRA-PAF - APAF (Pappone) - CAFCOAF (Stabile) - Krittayaphong - ThermoCool AF - Oral - Forleo - Lakkireddy - CABANA - STOP-AF
catheter ablation vs control | No demonstrated result suggested death or hospitalization for cardiac causes by 17% (not demonstrated) suggested Atrial fibrillation recurrence by 47% (not demonstrated) suggested atrial tachyarrhythmia recurrence free survival by 253% (not demonstrated) suggested Freedom from arrhythmia at 12 months per protocol by 299% (not demonstrated) suggested freedom from arrhythmia at 12 months - worst case by 275% (not demonstrated) suggested Freedom from arrhythmia at 12 months - ITT by 155% (not demonstrated) suggested Symptomatic Atrial Arrhythmia recurrence by 76% (not demonstrated) suggested Any Atrial Arrhythmia Recurrence by 71% (not demonstrated) suggested Adverse events by 52% (not demonstrated) |
All type of patients: 2 trials - VTACH - SMASH-VT
catheter ablation before ICD vs no ablation | No demonstrated result suggested VT or VF by 39% (not demonstrated) suggested hospitalisation for cardiovascular causes by 45% (not demonstrated) suggested Appropriate ICD shock by 49% (not demonstrated) suggested ICD events by 62% (not demonstrated) |
All type of patients: 2 trials - VTACH - SMASH-VT
catheter ablation before ICD vs no ablation | No demonstrated result suggested VT or VF by 39% (not demonstrated) suggested hospitalisation for cardiovascular causes by 45% (not demonstrated) suggested Appropriate ICD shock by 49% (not demonstrated) suggested ICD events by 62% (not demonstrated) |