Isosorbide dinitrate nitrates

Acute myocardial infarction

All type of patients:  4 trials  - ISIS-4 - Hildebrandt - Hargreaves - Fitzgerald

isosorbide dinitrate vs placebo

No demonstrated result

isosorbide mononitrate vs placebo

No demonstrated result

suggested early death by 9% (not demonstrated)

Heart failure

All type of patient:  2 trials  - NICE (Lewis) - Franciosa

isosorbide dinitrate vs placebo

No demonstrated result