PTCA trial summary

Acute myocardial infarction

>6h from onset of symptoms: 7 trials - TOMIIS - Horie et al - TOAT - DECOPI - Silva et al - OAT - TOSCA-2

No demonstrated result

All type of patients: 27 trials - TAMI 1 pilot - ECSG - SWIFT - SIAM - TIMI 2 - Guerci - Van den Brand - TOPS - TIMI II-A (defered) - TAMI-5 (Califf) - SHOCK (Hochman) - Ellis - Vermeer - Erbel - MERLIN (Sutton) - SWISS-SMASH - TIMI 2A - Belenkie - Topol - TAMI 6 - Barbash - MAASTRICHT (Vermeer) - PRAGUE-1 - AIR-PAMI - CAPTIM - DANAMI-2 - PRAGUE-2

No demonstrated result

Major bleeding by 143% (harmful effect)

No demonstrated result

suggested reinfarction by 64% (not demonstrated)

suggested death, reinfarctus, stroke by 41% (not demonstrated)

No demonstrated result

Emergency CABG by 137% (harmful effect)

suggested CABG by 31% (not demonstrated)

Failed fibrinolysis (rescue PCI): 5 trials - REACT (rescue PCI) - MERLIN - RESCUE II - RESCUE - Belenkie

No demonstrated result

suggested stroke (fatal and non fatal) by 370% (not demonstrated)

suggested Minor bleeding by 380% (not demonstrated)

Failed fibrinolysis (rescue revascularisation): 5 trials - REACT (rescue PCI) - MERLIN - RESCUE II - RESCUE - Belenkie

No demonstrated result

suggested stroke (fatal and non fatal) by 370% (not demonstrated)

suggested Minor bleeding by 380% (not demonstrated)

Late reperfusion: 7 trials - TOMIIS - Horie et al - TOAT - DECOPI - Silva et al - OAT - TOSCA-2

No demonstrated result

Patients in cardiogenic shock: 2 trials - SHOCK (Hochman) - SWISS-SMASH

No demonstrated result

Coronary artery disease

All type of patient: 17 trials - RITA 2 - ACME - Sievers - MASS - BARI - MASS - CABRI - EAST - GABI - Lausanne - RITA - ERACI - Toulouse - ACME 2 (Folland) - ACIP - INSPIRE - SWISSI II

No demonstrated result

suggested Angina (grade 2 or worse) in first year by 60% (not demonstrated)

suggested CABG by 1461% (not demonstrated)

No demonstrated result

See more clinical conditions

Stable angina

All type of patient: 17 trials - RITA 2 - ACME - Sievers - MASS - BARI - MASS - CABRI - EAST - GABI - Lausanne - RITA - ERACI - Toulouse - ACME 2 (Folland) - ACIP - INSPIRE - SWISSI II

No demonstrated result

suggested Angina (grade 2 or worse) in first year by 60% (not demonstrated)

suggested CABG by 1461% (not demonstrated)

No demonstrated result

See more clinical conditions

Multivessels disease: 9 trials - RITA 2 - BARI - CABRI - EAST - GABI - RITA - ERACI - Toulouse - ACME 2 (Folland)

No demonstrated result

suggested Angina (grade 2 or worse) in first year by 60% (not demonstrated)

suggested CABG by 1513% (not demonstrated)

No demonstrated result

suggested PTCA by 33% (not demonstrated)

Single vessel disease: 5 trials - ACME - Sievers - MASS - MASS - Lausanne

No demonstrated result

suggested CABG by 992% (not demonstrated)

No demonstrated result

suggested Angina by 39% (not demonstrated)

PTCA all percutaneous coronary intervention (PTCA, BMS, DES)

Acute myocardial infarction

Coronary artery disease

Stable angina