| rt-PA vs no fibrinolysis | No demonstrated result | | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
|---|
| recurrence of pulmonary embolism | 0.23 [0.03 1.54] | p=1.00 | 0 | 137 | 2 | PAIMS 2,Goldhaber, | | All cause death | 0.75 [0.11 5.19] | p=1.00 | 0 | 137 | 2 | PAIMS 2,Goldhaber, | | Minor bleeding | 2.20 [0.52 9.23] | p=1.00 | 0 | 36 | 1 | PAIMS 2, | | Major bleeding | 1.88 [0.43 8.24] | p=1.00 | 0 | 137 | 2 | PAIMS 2,Goldhaber, |
TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |
| rt-PA vs placebo | No demonstrated result suggested Minor bleeding by 1036% (not demonstrated) | | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
|---|
| recurrence of pulmonary embolism | 1.11 [0.30 4.20] | p=1.00 | 0 | 314 | 2 | Levine,Konstantinides, | | All cause death | 1.62 [0.45 5.80] | p=1.00 | 0 | 327 | 3 | PIOPED,Levine,Konstantinides, | | Minor bleeding | 11.36 [1.37 94.15] | p=0.04 | 0 | 58 | 1 | Levine, | | Major bleeding | 0.43 [0.08 2.27] | p=1.00 | 0 | 327 | 3 | PIOPED,Levine,Konstantinides, |
TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |
