alteplase vs primary intervention | No demonstrated result suggested Initial TIMI 3 flow by 153% (not demonstrated) | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
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Initial TIMI 3 flow | 2.53 [1.77 3.63] | p=0.04 | 0 | 749 | 2 | LIMI (Vermeer),PACT (Ross,), | Final TIMI 3 flow | 0.94 [0.46 1.89] | p=1.00 | 0 | 440 | 2 | LIMI (Vermeer),PACT (Ross,), | urgent target vessel revascularisation | 6.08 [0.71 51.81] | p=1.00 | 0 | 149 | 1 | LIMI (Vermeer), | Non fatal MI | 1.39 [0.57 3.37] | p=1.00 | 0 | 755 | 2 | LIMI (Vermeer),PACT (Ross,), | All cause death | 1.14 [0.56 2.33] | p=1.00 | 0 | 755 | 2 | LIMI (Vermeer),PACT (Ross,), | Major bleeding | 1.05 [0.59 1.85] | p=1.00 | 0 | 755 | 2 | LIMI (Vermeer),PACT (Ross,), | TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |