| vitamin C vs placebo | No demonstrated result suggested ischemic stroke by 15% (not demonstrated) | | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
|---|
| cardiovascular events | 1.00 [0.91 1.09] | p=1.00 | 0 | 22812 | 2 | WACS vitamin C,PHS II vitamin C, | | Cardiovascular death | 1.04 [0.91 1.19] | p=1.00 | 0 | 22812 | 2 | WACS vitamin C,PHS II vitamin C, | | stroke (fatal and non fatal) | 0.88 [0.76 1.01] | p=1.00 | 0 | 22812 | 2 | WACS vitamin C,PHS II vitamin C, | | ischemic stroke | 0.85 [0.73 1.00] | p=0.04 | 0 | 22812 | 2 | WACS vitamin C,PHS II vitamin C, | | Coronary event | 1.04 [0.82 1.33] | p=1.00 | 0 | 8171 | 1 | WACS vitamin C, | | Coronary death | no data | | Non fatal MI | 1.09 [0.84 1.40] | p=1.00 | 0 | 8171 | 1 | WACS vitamin C, | | All cause death | 1.05 [0.97 1.14] | p=1.00 | 0 | 22812 | 2 | WACS vitamin C,PHS II vitamin C, | | Non fatal stroke | 0.87 [0.68 1.11] | p=1.00 | 0 | 8171 | 1 | WACS vitamin C, | | Haemmorhagic stroke | 0.98 [0.64 1.49] | p=1.00 | 0 | 22812 | 2 | WACS vitamin C,PHS II vitamin C, |
TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |
