antioxydants
Trials Results

Beta carotene - Vitamin c - Vitamin e

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

cardiovascular prevention

beta carotene
SCP beta carotene, 1990beta caroteneplaceboNegative
ATBC beta carotene, 1994beta caroteneplacebo Exploratory -
CARET beta carotene, 1996beta caroteneplacebo Low risk of bias Negative
PHS beta carotene, 1996beta caroteneplacebo Low risk of bias Suggesting
ATBC 2nd prev subgroup (b carotene), 1998beta caroteneplacebo Exploratory Negative
NSCP (Green) beta carotene, 1999beta caroteneplacebo Low risk of bias Negative
WHS beta carotene, 1999beta caroteneplacebo Low risk of bias NegativeNCT00000479
WACS beta-caroten, 2007beta caroteneplacebo Low risk of bias NegativeNCT00000541
vitamin c
WACS vitamin C, 2007vitamin CplaceboNegativeNCT00000541
PHS II vitamin C, 2008vitamin Cplacebo Low risk of bias NegativeNCT00270647
vitamin e
Linxian, 1993vitamin EplaceboNegative
ATBC vitamin E, 1994vitamin Eplacebo Exploratory Suggesting
CHAOS, 1996vitamin Eplacebo Exploratory Suggesting
ATBC 2nd prev subgroup (vitamin E), 1998vitamin Eplacebo Exploratory Negative
GISSI, 1999vitamin Econtrol Risk of bias Negative
HOPE, 2000vitamin Eplacebo Low risk of bias Negative
ASAP, 2000vitamin Eplacebo Exploratory Negative
SPACE, 2000vitamin Eplacebo Low risk of bias Suggesting
AREDS, 2001vitamin Eplacebo Exploratory Negative
PPP, 2001vitamin Econtrol Risk of bias Negative
HOPE renal insufficiency subgroup, 2004vitamin Eplacebo Exploratory Negative
WHS vitamin E, 2005vitamin Eplacebo Exploratory NegativeNCT00000479
WACS vitamin E, 2007vitamin Eplacebo Low risk of bias NegativeNCT00000541
PHS II vitamin E, 2008vitamin Eplacebo Low risk of bias Negative NCT00270647

peripheral vascular diseases

vitamin e
Hamilton, 1953placebo -
Livingstone, 1958placebo -



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