renin inhibitor

Aliskiren

TrialStudied treatmentControl treatmentpatientsROBResultNCT

heart failure

aliskiren
ASTRONAUT, 2013Aliskirenplacebo Low risk of bias - NCT00894387
ATMOSPHERE ongoing aliskirenEnalapril Low risk of bias - NCT00853658

hypertension

aliskiren
AVOID, 2008aliskirenplacebo Exploratory NegativeNCT00097955
Andersen, 2008aliskirenramipril Exploratory -
Schmieder (vs HCTZ), 2009aliskirenhydrochlorothiazide Exploratory Negative
ALLAY, 2009aliskirenlosartan Exploratory NegativeNCT00219141