niraparib versus placebo | |||
ENGOT-OV16/NOVA non-gBRCA, NCT01847274 | niraparib (300 mg) once daily versus placebo | patients with platinum-sensitive, recurrent ovarian cancer | double-blind |
ENGOT-OV16/NOVA gBRCA, 2017 NCT01847274 | niraparib (300 mg) once daily as maintenance treatment versus placebo | patients with platinum-sensitive, recurrent ovarian cancer with germline BRCA mutation | double-blind |
olaparib versus placebo | |||
SOLO2/ENGOT-Ov21, NCT01874353 | olaparib 300 mg in two 150 mg tablets, twice daily versus placebo | patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation | double-blind international |
olaparid versus placebo | |||
Ledermann, 2012 NCT00753545 | olaparib, at a dose of 400 mg twice daily versus placebo | patients with platinum-sensitive, relapsed, high-grade serous ovarian cancer with or without BRCA1 or BRCA2 germline mutations, who had received two or more platinum-based regimens and had had a partial or complete response to their most recent platinum-based regimen | double-blind |