Rosuvastatin cholesterol lowering intervention
systematic review meta-analysis network meta-analysis
 

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathcardiovascular events

aortic stenosis  

ASTRONOMER, 2010   rosuvastatinplaceboaortic stenosisLow risk of bias -

atrial fibrillation  

GISSI HF (subgroup and ancillary study), 2009    NCTrosuvastatin placeboLow risk of bias negative

cardiovascular prevention  

METEOR, 2007      NCTrosuvastatinplacebodiabeticExploratory negative∞%
JUPITER, 2008    NCTrosuvastatinplaceboprimary preventionLow risk of bias conclusive -20%-47%
CORONA, 2007      NCTrosuvastatinplaceboheart failureLow risk of bias negative-5%-6%
Krum, 2007     rosuvastatinplaceboheart failureLow risk of bias negative-23%
GISSI-HF rosuvastatine, 2008      NCTrosuvastatinplaceboheart failureLow risk of bias negative 2%-2%
AURORA, 2009       rosuvastatinplaceboLow risk of bias negative-4%-3%
JUPITER (elderly sub group), 2009     rosuvastatinplaceboelderly elderly Low risk of bias suggesting-20%-39%
ASTRONOMER, 2010   rosuvastatinplaceboaortic stenosisLow risk of bias -
JUPITER (women subgroup) , 2008     RosuvastatinplacebowomenExploratory suggesting-23%-45%
HOPE 3, 2016      NCTrosuvastatinplaceboprimary preventionLow risk of bias conclusive-7%-24%

heart failure  

CORONA, 2007      NCTrosuvastatinplaceboheart failureLow risk of bias negative-5%-6%
Krum, 2007     rosuvastatinplaceboheart failureLow risk of bias negative-23%
GISSI-HF rosuvastatine, 2008      NCTrosuvastatinplaceboheart failureLow risk of bias negative 2%-2%

venous thrombosis  

VanGogh extension, 2007      NCTidraparinuxdiscontinuationsuggesting



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