Amiodarone antiarrythmic drugs
systematic review meta-analysis network meta-analysis
 

Aratac - Tachydaron - Rytmarone - Ortacrone - Corbionax - Braxan - Amiohexal - Amiodarona - Trangorex - Kordaron - Amiodarex - Cordarex - Cordarone - Amiobeta      

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathAdverse events leading to treatment discontinuation

atrial fibrillation  

Channer, 2004     amiodaroneplaceboLow risk of bias suggesting398%
GEFACA, 2001   amiodaroneplaceboLow risk of bias suggesting∞%
Kochiadakis (amiodarone vs placebo), 2000       amiodaroneplacebosuggesting∞%
SAFE-T (amiodarone vs placebo), 2005       amiodaroneplaceboLow risk of bias suggesting114%
AFFIRM Substudy (amiodarone vs class I drugs), 2003     amiodaroneclass I drugsRisk of bias suggesting-58%-67%
AFFIRM Substudy (sotalol vs class I drugs), 2003     amiodaroneclass I drugs -
Villani, 1992   amiodaronedisopyramidesuggesting-65%
Kochiadakis a, 2004       amiodaronepropafenonenegative 774%
Vitolo, 1981   amiodaronequinidinesuggesting-7%
AFFIRM Substudy (amiodarone vs sotalol), 2003     amiodaronesotalolsuggesting-40%-17%
Kochiadakis (amiodarone vs sotalol), 2000     amiodaronesotalol -
SAFE-T (amiodarone vs sotalol), 2005     amiodaronesotalolLow risk of bias -

cardiac arrest  

ARREST, 1999     amiodaroneplaceboLow risk of bias suggesting
ALIVE, 2002     amiodaronelidocaineLow risk of bias suggesting-2%

heart failure  

EPAMSA, 1985   amiodaroneno treatmentsuggesting-61%
GESICA, 1994   amiodaroneno treatmentsuggesting-28%
Hamer, 1989   amiodaroneplaceboLow risk of bias suggesting-25%
Nicklas, 1991   amiodaroneplaceboLow risk of bias negative54%
STATCHF, 1995     amiodaroneplaceboLow risk of bias negative-6%
AMIOVIRT, 2003     amiodaroneICDnegative14%

post myocardial infarction  

BASIS, 1990   early amiodaronecontrolsuggesting-59%
Navarro-Lopez, 1993   early amiodaronecontrolnegative-52%
CAMIAT , 1991   early amiodaroneplaceboLow risk of bias negative-18%
Ceremuzynski, 1992   early amiodaroneplaceboLow risk of bias negative-37%
Hockings, 1987     early amiodaroneplaceboLow risk of bias negative94%



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